Area Farmacología, Departamento de Fisiopatología. Facultad de Ciencias Veterinarias. Universidad Nacional del Centro de la Provincia de Buenos Aires. Campus Universitario, (7000) Tandil.


  1. LIFSCHITZ, S. NAVA, A. MANGOLD, F. IMPERIALE , M. BALLENT, J. CANEVARI C. LANUSSE. Eprinomectin accumulation in Rhipicephalus (Boophilus) microplus: Pharmacokinetic and efficacy assessment. Veterinary Parasitology, 215, 11-16, 2016.

BALLENT M, VIRKEL G, MATÉ L, VIVIANI P, LANUSSE C, LIFSCHITZ A. Hepatic biotransformation pathways and ruminal metabolic stability of the novel anthelmintic monepantel in sheep and cattle.Journal of Veterinary Pharmacology and Therapeutics.. doi: 10.1111/jvp.12296.

GAMBOA GV, PALMA SD, LIFSCHITZ A, BALLENT M, LANUSSE C, PASSIRANI C, BENOIT JP, ALLEMANDI DA. Ivermectin-loaded lipid nanocapsules: toward the development of a new antiparasitic delivery system for veterinary applications.Parasitology Research,. DOI 10.1007/s00436-016-4937-1

MAHNKE H, BALLENT M, BAUMANN S, IMPERIALE F, VON BERGEN M, LANUSSE C, LIFSCHITZ AL, HONSCHA W, HALWACHS S. The ABCG2 Efflux Transporter in the Mammary Gland Mediates Veterinary Drug Secretion across the Blood-Milk Barrier into Milk of Dairy Cows. Drug Metab Dispos. 44, 700-8.

LATORRE ME, LIFSCHITZ AL, PURSLOW PP. New recommendations for measuring collagen solubility Meat Science.118:78-81.

Karen E. Larsen, Adrián L. Lifschitz Carlos E. Lanusse , Guillermo L. Virkel. The herbicide glyphosate is a weak inhibitor of acetylcholinesterase in rats. Environmental Toxicology and Pharmacology, 45:41-44.

Carlos E. Lanusse, Luis I. Alvarez, Adrián L. Lifschitz. Gaining insights into the pharmacology of anthelmintics using Haemonchus contortus as a model nematode En Advance in Parasitology: Haemonchus contortus and haemonchosis – past, present and future trends. In press.

LARSEN K, NAJLE R, LIFSCHITZ A, MATÉ ML, LANUSSE C, VIRKEL GL. Effects of sublethal exposure to a glyphosate-based herbicide formulation on metabolic activities of different xenobiotic metabolizing enzymes in rats. International Journal of Toxicology. DOI: 10.1177/1091581814540481. 33, 307-318. 2015

  1. LLOBERAS, L. ALVAREZ, C. ENTROCASSO, BALLENT, M., G. VIRKEL, LUQUE, S., C. LANUSSE, A. LIFSCHITZ. Comparative pharmacokinetic and pharmacodynamics response of single and double intraruminal doses of ivermectin and moxidectin in nematode-infected lambs. New Zealand Veterinary Journal, 131, 304-309, 2015

MATÉ ML, BALLENT M, LARSEN K, LIFSCHITZ A, LANUSSE C, VIRKEL G. Gene expression and enzyme function of two cytochrome P450 3A isoenzymes in rat and cattle precision cut liver slices, Xenobiotica: the fate of foreign compounds in biological systems, 45, 563-570, 2015

LANUSSE C., LIFSCHITZ A., ALVAREZ, L. Basic and clinical pharmacology contribution to extend anthelmintic molecules lifespan. Veterinary Parasitology, 212, 35-46, 2015.

ALVAREZ, L., SUAREZ, G., CEBALLOS, L., MORENO, L., CANTÓN, C., LIFSCHITZ, A., MATE, L., BALLENT, M., VIRKEL, G., LANUSSE, C. Integrated assessment of ivermectin pharmacokinetics, efficacy against resistant Haemonchus contortus and P-glycoprotein expression in lambs treated at three different dosage levels. Veterinary Parasitology, 210, 53-63, 2015

WILKENS M.R.,. MATE L.M , SCHNEPEL N., KLINGER S., MUSCHER-BANSE A.S. , BALLENT M., VIRKEL G. LIFSCHITZ A. Influence of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on expression of Pglycoprotein and cytochrome P450 3A in sheep. Journal of Steroid Biochemistry & Molecular Biology, in press, DOI

IEZZI, S; LIFSCHITZ, A; SALLOVITZ JM; LANUSSE C; IMPERIALE F. Impacto de los residuos de ivermectina en los procesos tecnológicos de la leche y sus derivados. Rev vet 26 (2): 2015.

LANUSSE C, ALVAREZ L, LIFSCHITZ A. Pharmacological knowledge and sustainable anthelmintic therapy in ruminants. Vet. Parasitol. 204, 18-33 , 2014

LIFSCHITZ, A., BALLENT, M., VIRKEL, G., SALLOVITZ, J., VIVIANI, P., MATE, L., LANUSSE. C. Accumulation of monepantel and its sulphone derivative in tissues of nematode location in sheep – pharmacokinetic support to its excellent nematodicidal activity- Vet. Parasitol. 203, 120-126,2014.

BALLENT, M., MATÉ, L., VIRKEL, G., SALLOVITZ, J., VIVIANI, P., LANUSSE, C., LIFSCHITZ, A. Intestinal drug transport: ex vivo evaluation of the interactions between ABC transporters and anthelmintic molecules. Journal of Veterinary Pharmacology and Therapeutics, 37, 332-337, 2014.

  1. VIRKEL, A. LIFSCHITZ, J. SALLOVITZ, L. MATÉ, C. FARÍAS, C. Lanusse. In vitro and in vivo assessment of the benzydamine-mediated interference with the hepatic S-oxidation of the anthelminticalbendazole in sheep. Small Ruminant Research, 120, 142-149, 2014
  2. IEZZI, A. LIFSCHITZ, J. SALLOVITZ, P. NEJAMKIN, M. LLOBERAS, J. MANAZZA, C. LANUSSE, F. IMPERIALE. Closantel plasma and milk disposition in dairy goats: Assessment of drug residues in cheese and ricotta. Journal of Veterinary Pharmacology and Therapeutics, 37, 589-594.

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